Are you a BSc or MSc graduate with computational / statistical background looking for a challenge in cancer genomics and CRISPR?
The Project: Finding therapeutic targets in cancer remains a grand challenge in biomedical research. Our genome contains many thousands of long noncoding RNA (lncRNA) genes representing a rich and unexplored source of drug targets. Our lab has adapted CRISPR-Cas9 technology to powerful screens for these cancer-causing lncRNAs. This approach rests on a foundation of informatic and statistical analyses. Furthermore, candidate lncRNAs are investigated by integrative analysis with diverse clinical and genomic datasets. Both are the objective of this PhD project ...Read more