BioInformatics in Torun with a session Bioinformatics Fights Viruses — Program

BIT21 with a session BFV AGENDA, June 24th, 2021,

All hours Warsaw time. (Time in Warsaw, GMT+2)

SESSION 1 (chair:  Prof. Wieslaw Nowak )

13:00 Prof. Danuta Mossakowska-Earnshaw
Malopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland
“Application of informatics to decision making in drug discovery”

13:30  Prof. Joanna Trylska
CENT – University of Warsaw, Warsaw , Poland
“Crowding affects the activity and dynamics of the NS3/4A protease of the hepatitis C virus”

14:00  Dr Mateusz Sikora
Max Planck Institute of Biophysics, Frankfurt /am Main, Germany
and  University of Vienna, Vienna, Austria
"Protein flexibility and glycan dynamics of the SARS-CoV-2 spike: clues on infection mechanism and epitope masking"

14:30 Dr Lukasz Pepłowski
Institute of Physics, N. Copernicus University in Torun, Poland
“Nanomechanical aspects of nanobodies-protein S SARS-CoV-2 virus complexes – a computational study”

14:45 – end of Session I


SESSION 2 (Chair: prof. Aleksandra GRUCA)

15:00 KEYNOTE: Prof. Jarek Meller
Cincinnati Children`s Hospital Medical Center and University of Cincinnati, Cincinnati, USA
“Accelerating Drug Discovery and Repurposing by Combining Transcriptional Signature Connectivity with Docking”

15:30 Jarosław Synak
Institute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan, Poland
“Virxicon: a lexicon of viral sequences”

15:45 Yojana Gadiya

Fraunhofer Institute for Translation and Medicine Pharmacology, Screening Port (ITMP)
“Modelling COVID-19 pathophysiology through knowledge graphs  and its application”

16:00 Michał Kowalski, Alina Frolova
Malopolska Center of Biotechnology, Jagiellonian University, Cracow, Poland
Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine
„In silico evaluation of SARS-CoV-2 primers performance”.

16:15 Bartlomiej  Szawulak
Poznan University of Medical Sciences, Poznan, Poland
"The influence of SARS-CoV-2 infection on the RAA system".

16:30 end of Session II

SESSION 3 Flash Talks (Chair: prof. Witold RUDNICKI)

17:00 Dr Magdalena A. Machnicka
Institute of Informatics, University of Warsaw
“Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas”

17:15 Ługowska Magdalena
Silesian Technical University, Gliwice, Poland
“Ligand dissociation pathway investigation by τ-random acceleration molecular dynamics (τRAMD)”

17:20 Beata Niklas
N. Copernicus University, Torun, Poland
“Stop the biting: tracking the insecticide-mediated allosteric changes in muscarinic acetylcholine receptors and design of selective, photoactivated bitopic ligands”

17:25 Jakub Wojciechowski
Wrocław University of Science and Technology, Wroclaw, Poland
„PATH to prediction of long amyloid and functional amyloid peptides”

17:30  Sylwia Czach
N. Copernicus University, Torun, Poland
“Docking to purinergic P2X7 receptor as a part of the battle against glioblastoma”

17:35 Julia Berdychowska
N. Copernicus University, Torun, Poland
„Molecular dynamics as a tool to improve thermostability of  NHase - biotechnologically important enzyme”

17:40 Thiliban Manivarma
N. Copernicus University, Torun, Poland
“Hot spots, proteins, and machine learning”

17:45 Flash talks sessions end

18:00 Prof. Marta Luksza
Icahn School of Medicine, Mount Sinai, NYC,USA
“Predicting the evolution of influenza for vaccine composition design”

18:30 Prof. K. Kuczera
Chemistry and Molecular Biosciences, University of Kansas, Lawrence, USA
“Length Dependent Folding Kinetics of Alanine-Based Helical Peptides from Optimal Dimensionality Reduction”

19:00 KEYNOTE: Prof. Gennady M. Verkhivker
Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine CA, USA
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego CA, USA
“Conformational  landscaping and mutational cartography of the SARS-CoV-2  proteins: probing allosteric mechanisms of spike functions and antibody-induced neutralization”

19:30 BIT21- BFV2 Conference ends (summary: Prof. WIESLAW NOWAK, NCU/PTBI)